EtS is a direct biomarker of alcohol ingestion that is not susceptible to degradation by bacteria hydrolysis.Ĭonfirmation of EtG results is done by Liquid Chromatography-Mass Spectrometry and Liquid Chromatography-Tandem Mass Spectrometry (LC/MS/MS, which is the most sensitive and, therefore, preferred method) gas chromatography-mass spectrometry (GC/MS) or Liquid Chromatography-Mass Spectrometry (LC/MS).ĮtG, in conjunction with EtS, is a scientifically accepted biomarker to show exposure to alcohol. It can also be detected in urine, plasma, hair and body tissue.Įthyl sulfate (EtS) is tested in conjunction with EtG for confirmation purposes. It’s a highly sensitive and specific biomarker and can be detected anywhere from four to five days after alcohol consumption as opposed to eight to 12 hours when testing for ethanol, making it useful for situations where a person needs to be monitored on a continuous basis. Alere is a provider of popular bulk drug test supplies like the 5 Panel iCup Urine Drug Test Cup with Adulterants.ĮtG is a direct, non-volatile, water-soluble, metabolite of ethanol. Pat Pizzo, Director of Toxicology at Alere Toxicology, presented a webinar entitled “ EtG & EtS: A New Way to Look at Alcohol Testing" to explain the ins and outs of EtG and EtS testing.
Most of these detectable excretory products in urine can be detected for short period of time. Metabolic excretion by conversion of ethyl glucuronide and ethyl sulfate which are both eliminated through urination.Metabolic excretion by conversion to acetaldehyde.Direct excretion of ethanol (5-10%) in urine, breath, and sweat.However, with EtG testing, it is Ethyl Glucuronide that is tested for.Īn advantage of testing for EtG over ethanol is that EtG breaks down or metabolizes without oxidizing, creating an analyte that can be measured for a much longer period than ethanol can be measured for.Įthanol can be excreted from the body in several ways, namely: With more traditional forms of alcohol testing, like breath, saliva or standard urine testing, it’s ethanol that is tested for.
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